Donata Vercelli, MD

Professor, Cellular and Molecular Medicine
Director, Molecular Genomics- A2DRC
Director, Arizona Center for the Biology of Complex Diseases
Professor, BIO5 Institute

Research Interest:

Genetic, epigenetic and environmental mechanisms that control susceptibility to complex lung diseases.

Selected Publications


Vercelli D. "Microbiota and human allergic diseases: the company we keep." Curr Opin Immunol. 2021;72:215-220. PMCID: PMC8578191  PMID: 34182271

Lynch SV, Vercelli D. "Microbiota, Epigenetics, and Trained Immunity. Convergent Drivers and Mediators of the Asthma Trajectory from Pregnancy to Childhood." Am J Respir Crit Care Med. 2021;203(7):802-808. PMCID: PMC8017579  PMID: 33493428

Pivniouk V, Gimenes-Junior JA, Ezeh P, et al. "Airway administration of OM-85, a bacterial lysate, blocks experimental asthma by targeting dendritic cells and the epithelium/IL-33/ILC2 axis." J Allergy Clin Immunol. 2021. PMID: 34560105

Pivniouk V, Pivniouk O, DeVries A, et al. "The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression." J Allergy Clin Immunol. 2021. PMCID: PMC8660661  PMID: 34902435


Giammò A, Geretto P, Ammirati E, et al. "Urethral bulking with Bulkamid: An analysis of efficacy, safety profile, and predictors of functional outcomes in a single-center cohort." Neurourol Urodyn. 2020;39(5):1523-1528.

Pivniouk V, Junior JAntonio Gi, Honeker LK, Vercelli D. "The role of innate immunity in asthma development and protection: Lessons from the environment." Clin Exp Allergy. 2020;50(3):282-290.

Morin A, McKennan CG, Pedersen C-ET, et al. "Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age." J Allergy Clin Immunol. 2020;146(6):1358-1366. PMCID: PMC7821422  PMID: 32693091

Kimura H, Francisco D, Conway M, et al. "Type 2 inflammation modulates ACE2 and TMPRSS2 in airway epithelial cells." J Allergy Clin Immunol. 2020;146(1):80-88.e8. PMCID: PMC7227558  PMID: 32422146


Carr TF, Beamer PI, Rothers J, et al. "Prevalence of Asthma in School Children on the Arizona-Sonora Border." J Allergy Clin Immunol Pract. 2017;5(1):114-120.e2. PMCID: PMC5222738  PMID: 27544711

DeVries A, Wlasiuk G, Miller SJ, et al. "Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers." J. Allergy Clin. Immunol.. 2017;140(2):534-542. PMCID: PMC5479765  PMID: 28011059

Clinical Trials

Study Title (link to more info on this site)sort descending Link to Study Trial Status Principal Investigator
BEAMS Current Trial - Enrolling Paloma Beamer, PhD, Dean Billheimer, PhD, Tara F. Carr, MD, Darren A. Cusanovich, PhD, Fernando Martinez, MD, Donata Vercelli, MD, Anne L. Wright, PhD
OM-Pharma Current Trial - Enrolling Donata Vercelli, MD