Genetic, epigenetic and environmental mechanisms that control susceptibility to complex lung diseases.
DeVries A, McCauley K, Fadrosh D, et al. "Maternal prenatal immunity, neonatal trained immunity, and early airway microbiota shape childhood asthma development." Allergy. 2022;77(12):3617-3628. PMCID: PMC9712226 PMID: 35841380
Vercelli D. "Microbiota and human allergic diseases: the company we keep." Curr Opin Immunol. 2021;72:215-220. PMCID: PMC8578191 PMID: 34182271
Lynch SV, Vercelli D. "Microbiota, Epigenetics, and Trained Immunity. Convergent Drivers and Mediators of the Asthma Trajectory from Pregnancy to Childhood." Am J Respir Crit Care Med. 2021;203(7):802-808. PMCID: PMC8017579 PMID: 33493428
Pivniouk V, Gimenes-Junior JA, Ezeh P, et al. "Airway administration of OM-85, a bacterial lysate, blocks experimental asthma by targeting dendritic cells and the epithelium/IL-33/ILC2 axis." J Allergy Clin Immunol. 2021. PMID: 34560105
Pivniouk V, Pivniouk O, DeVries A, et al. "The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression." J Allergy Clin Immunol. 2021. PMCID: PMC8660661 PMID: 34902435
Pivniouk V, Junior JAntonio Gi, Honeker LK, Vercelli D. "The role of innate immunity in asthma development and protection: Lessons from the environment." Clin Exp Allergy. 2020;50(3):282-290.
Kimura H, Francisco D, Conway M, et al. "Type 2 inflammation modulates ACE2 and TMPRSS2 in airway epithelial cells." J Allergy Clin Immunol. 2020;146(1):80-88.e8. PMCID: PMC7227558 PMID: 32422146
Giammò A, Geretto P, Ammirati E, et al. "Urethral bulking with Bulkamid: An analysis of efficacy, safety profile, and predictors of functional outcomes in a single-center cohort." Neurourol Urodyn. 2020;39(5):1523-1528.
Morin A, McKennan CG, Pedersen C-ET, et al. "Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age." J Allergy Clin Immunol. 2020;146(6):1358-1366. PMCID: PMC7821422 PMID: 32693091
DeVries A, Wlasiuk G, Miller SJ, et al. "Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers." J. Allergy Clin. Immunol.. 2017;140(2):534-542. PMCID: PMC5479765 PMID: 28011059
Carr TF, Beamer PI, Rothers J, et al. "Prevalence of Asthma in School Children on the Arizona-Sonora Border." J Allergy Clin Immunol Pract. 2017;5(1):114-120.e2. PMCID: PMC5222738 PMID: 27544711
Study Title (link to more info on this site) |
Link to Study | Trial Status | Principal Investigator |
|---|---|---|---|
| BEAMS | view | Current Trial - Enrolling | Paloma Beamer, PhD, Dean Billheimer, PhD, Tara F. Carr, MD, Darren A. Cusanovich, PhD, Fernando Martinez, MD, Donata Vercelli, MD |
| OM-Pharma | view | Current Trial - Enrolling | Donata Vercelli, MD |
