Donata Vercelli, MD

Professor, Cellular and Molecular Medicine
Director, Molecular Genomics- A2DRC
Director, Arizona Center for the Biology of Complex Diseases
Professor, BIO5 Institute

Research Interest:

Genetic, epigenetic and environmental mechanisms that control susceptibility to complex lung diseases.

Selected Publications


DeVries A, McCauley K, Fadrosh D, et al. "Maternal prenatal immunity, neonatal trained immunity, and early airway microbiota shape childhood asthma development." Allergy. 2022;77(12):3617-3628. PMCID: PMC9712226  PMID: 35841380


Pivniouk V, Pivniouk O, DeVries A, et al. "The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression." J Allergy Clin Immunol. 2021. PMCID: PMC8660661  PMID: 34902435

Vercelli D. "Microbiota and human allergic diseases: the company we keep." Curr Opin Immunol. 2021;72:215-220. PMCID: PMC8578191  PMID: 34182271

Lynch SV, Vercelli D. "Microbiota, Epigenetics, and Trained Immunity. Convergent Drivers and Mediators of the Asthma Trajectory from Pregnancy to Childhood." Am J Respir Crit Care Med. 2021;203(7):802-808. PMCID: PMC8017579  PMID: 33493428

Pivniouk V, Gimenes-Junior JA, Ezeh P, et al. "Airway administration of OM-85, a bacterial lysate, blocks experimental asthma by targeting dendritic cells and the epithelium/IL-33/ILC2 axis." J Allergy Clin Immunol. 2021. PMID: 34560105


Giammò A, Geretto P, Ammirati E, et al. "Urethral bulking with Bulkamid: An analysis of efficacy, safety profile, and predictors of functional outcomes in a single-center cohort." Neurourol Urodyn. 2020;39(5):1523-1528.

Morin A, McKennan CG, Pedersen C-ET, et al. "Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age." J Allergy Clin Immunol. 2020;146(6):1358-1366. PMCID: PMC7821422  PMID: 32693091

Pivniouk V, Junior JAntonio Gi, Honeker LK, Vercelli D. "The role of innate immunity in asthma development and protection: Lessons from the environment." Clin Exp Allergy. 2020;50(3):282-290.

Kimura H, Francisco D, Conway M, et al. "Type 2 inflammation modulates ACE2 and TMPRSS2 in airway epithelial cells." J Allergy Clin Immunol. 2020;146(1):80-88.e8. PMCID: PMC7227558  PMID: 32422146


DeVries A, Wlasiuk G, Miller SJ, et al. "Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers." J. Allergy Clin. Immunol.. 2017;140(2):534-542. PMCID: PMC5479765  PMID: 28011059

Carr TF, Beamer PI, Rothers J, et al. "Prevalence of Asthma in School Children on the Arizona-Sonora Border." J Allergy Clin Immunol Pract. 2017;5(1):114-120.e2. PMCID: PMC5222738  PMID: 27544711

Clinical Trials

Study Title (link to more info on this site)sort descending Link to Study Trial Status Principal Investigator
BEAMS Current Trial - Enrolling Paloma Beamer, PhD, Dean Billheimer, PhD, Tara F. Carr, MD, Darren A. Cusanovich, PhD, Fernando Martinez, MD, Donata Vercelli, MD
OM-Pharma Current Trial - Enrolling Donata Vercelli, MD