Step-Up Yellow Zone Inhaled Corticosteroids to Prevent Exacerbations (STICS)

Trial Status: 


The purpose of this study is to find the best yellow zone action plan strategy for children with asthma.  Most people with asthma use an action plan to guide their asthma treatment. Written asthma action plans are usually color-coded. “Green” means that asthma symptoms are well controlled. “Yellow” means that asthma symptoms are not well controlled and asthma treatment may need to change. “Red” means a severe worsening of symptoms. Red zone treatment is usually an oral corticosteroid like prednisone. Finding the best yellow zone strategy may prevent children from entering the red zone and having to take prednisone. The study is also trying to determine which yellow zone strategy leads to the least total corticosteroid (oral and inhaled) use for children with asthma. 


Children 5 years to 11 years of age may be eligible to join the study.

For more information, visit the AsthmaNet web site.


The National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)


AsthmaNet Network


Principal Investigator:

Fernando Martinez, MD

Contact Information:

Office: (520) 626-9543


Principal Investigator: 
Research Area: 
Clinical and Population Research