The Tucson Epidemiological Study of Airway Obstructive Disease (TESAOD) is a population-based prospective cohort study initiated in 1972 in Tucson, Arizona. The purpose of this study was to determine the natural history, etiology, and interrelationships of emphysema, chronic bronchitis, asthma, and related airway obstructive diseases. At study initiation, 3,805 Tucson residents between the ages of 6-95 years were enrolled. Due to study subjects getting married and having children of their own, study enrollment increased over the following 24 years to nearly 5,400.
Starting in 1972, questionnaires and blood samples were collected and pulmonary function testing and skin prick tests were performed in up to 14 surveys over a 35 year period. Of our 5,377 subjects, 1,033 (19%) have been classified as ever having COPD and 854 (16%) have been classified as ever having received a physician diagnosis of asthma. In addition, TESAOD has recently completed a comprehensive National Death Index search and has ascertained mortality information (including date and leading cause of death) for 1,997 deceased subjects as of January 2011.
Phenotype data for each TESAOD survey, numbers correspond to participants with data