Regents' Professor
Director, Asthma & Airway Disease Research Center
Swift-McNear Professor of Pediatrics
Research Interest:
Asthma and gene-environment interactions.
Fernando Martinez, MD
Selected Publications
2023
Guerra S, Ledford JG, Melén E, et al. "Creatine Kinase Is Decreased in Childhood Asthma." Am J Respir Crit Care Med. 2023;207(5):544-552. PMCID: PMC10870915 PMID: 35876143
Carr TF, Stern DA, Morgan W, Guerra S, Martinez FD. "Elevated Childhood Insulin-related Asthma Is a Risk Factor for Reduced Lung Function." Am J Respir Crit Care Med. 2023;207(6):790-792. PMCID: PMC10037476 PMID: 36521027
2022
Voraphani N, Stern DA, Zhai J, et al. "The role of growth and nutrition in the early origins of spirometric restriction in adult life: a longitudinal, multicohort, population-based study." Lancet Respir Med. 2022;10(1):59-71. PMID: 34843665
2021
Johnson CC, Havstad SL, Ownby DR, et al. "Pediatric asthma incidence rates in the United States from 1980 to 2017." J Allergy Clin Immunol. 2021;148(5):1270-1280. PMCID: PMC8631308 PMID: 33964299
Phipatanakul W, Mauger DT, Guilbert TW, et al. "Preventing asthma in high risk kids (PARK) with omalizumab: Design, rationale, methods, lessons learned and adaptation." Contemp Clin Trials. 2021;100:106228. PMCID: PMC7887056 PMID: 33242697
Ryan PH, Brokamp C, Blossom J, et al. "A distributed geospatial approach to describe community characteristics for multisite studies." J Clin Transl Sci. 2021;5(1):e86. PMCID: PMC8111696 PMID: 34007469
Johnson MDL, Younis US, Menghani SV, et al. "CC16 Binding to αβ Integrin Protects against Infection." Am J Respir Crit Care Med. 2021;203(11):1410-1418. PMCID: PMC8456541 PMID: 33326355
Hallmark B, Wegienka G, Havstad S, et al. "Chromosome 17q12-21 Variants Are Associated with Multiple Wheezing Phenotypes in Childhood." Am J Respir Crit Care Med. 2021;203(7):864-870. PMCID: PMC8017591 PMID: 33535024
Pivniouk V, Gimenes-Junior JA, Ezeh P, et al. "Airway administration of OM-85, a bacterial lysate, blocks experimental asthma by targeting dendritic cells and the epithelium/IL-33/ILC2 axis." J Allergy Clin Immunol. 2021. PMID: 34560105
Ortega VE, Daya M, Szefler SJ, et al. "Pharmacogenetic studies of long-acting beta agonist and inhaled corticosteroid responsiveness in randomised controlled trials of individuals of African descent with asthma." Lancet Child Adolesc Health. 2021;5(12):862-872. PMCID: PMC8787857 PMID: 34762840
2020
Guerra S, Lombardi E, Stern DA, et al. "Fetal Origins of Asthma: A Longitudinal Study from Birth to Age 36 Years." Am. J. Respir. Crit. Care Med.. 2020. PMID: 32649838
Chang EH, Willis AL, Romanoski CE, et al. "Rhinovirus Infections in Individuals with Asthma Increase ACE2 Expression and Cytokine Pathways Implicated in COVID-19." Am J Respir Crit Care Med. 2020;202(5):753-755. PMCID: PMC7462393 PMID: 32649217
Polverino F, Stern DA, Ruocco G, et al. "Comorbidities, Cardiovascular Therapies, and COVID-19 Mortality: A Nationwide, Italian Observational Study (ItaliCO)." Front Cardiovasc Med. 2020;7:585866. PMCID: PMC7583635
Kimura H, Francisco D, Conway M, et al. "Type 2 inflammation modulates ACE2 and TMPRSS2 in airway epithelial cells." J Allergy Clin Immunol. 2020;146(1):80-88.e8. PMCID: PMC7227558 PMID: 32422146
2019
Zhai J, Insel M, Addison KJ, et al. "Club Cell Secretory Protein Deficiency Leads to Altered Lung Function." Am. J. Respir. Crit. Care Med.. 2019;199(3):302-312. PMCID: PMC6363971 PMID: 30543455
Gerald JK, Hallmark B, Billheimer D, Martinez FD, Gerald LB. "Are Latino children of Mexican origin with asthma less responsive to inhaled corticosteroids than white children?" J Allergy Clin Immunol Pract. 2019.
Martinez FD. "Childhood Asthma Inception and Progression: Role of Microbial Exposures, Susceptibility to Viruses and Early Allergic Sensitization." Immunol Allergy Clin North Am. 2019;39(2):141-150. PMCID: PMC6613822 PMID: 30954166
Beamer PI, Furlong M, Lothrop N, et al. "CC16 Levels into Adult Life are Associated with Nitrogen Dioxide Exposure at Birth." Am. J. Respir. Crit. Care Med.. 2019. PMID: 30789752
2018
Lang JE, Fitzpatrick AM, Mauger DT, et al. "Overweight/obesity status in preschool children associates with worse asthma but robust improvement on inhaled corticosteroids." J. Allergy Clin. Immunol.. 2018;141(4):1459-1467.e2. PMID: 29273557
Wedzicha JA, Martinez FD. "Asthma: Upcoming Themed Issue." Am. J. Respir. Crit. Care Med.. 2018;198(5):549.
Chang EH, Stern DA, Willis AL, Guerra S, Wright AL, Martinez FD. "Early life risk factors for chronic sinusitis: A longitudinal birth cohort study." J. Allergy Clin. Immunol.. 2018;141(4):1291-1297.e2. PMCID: PMC5937937 PMID: 29355680
Vasquez MM, Zhou M, Hu C, Martinez FD, Guerra S. "Reply to Bush: Low Lung Function in Young Adult Life Is Associated with Early Mortality." Am. J. Respir. Crit. Care Med.. 2018;197(4):539. PMCID: PMC5821910 PMID: 28925717
Zhai J, Stern DA, Sherrill DL, et al. "Trajectories and Early Determinants of Circulating CC16 from Birth to Age 32 Years." Am. J. Respir. Crit. Care Med.. 2018;198(2):267-270. PMCID: PMC6058982 PMID: 29485918
Fitzpatrick AM, Bacharier LB, Guilbert TW, et al. "Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation." J Allergy Clin Immunol Pract. 2018.
Kothari PH, Qiu W, Croteau-Chonka DC, et al. "Role of local CpG DNA methylation in mediating the 17q21 asthma susceptibility gasdermin B (GSDMB)/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) expression quantitative trait locus." J. Allergy Clin. Immunol.. 2018;141(6):2282-2286.e6. PMCID: PMC5994185 PMID: 29374573
